Antimutagenicity and DT-diaphorase inducing activity of Gynostemma pentaphyllum Makino extract
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منابع مشابه
Antimutagenicity and DT-diaphorase inducing activity of Gynostemma pentaphyllum Makino extract.
The hot water extract of the herbal tea, Gynostemma pentaphyllum Makino, was not found to be mutagenic in Salmonella mutation assay with or without metabolic activation. However, the extract had both DT-diaphorase inducing activity in the murine hepatoma (Hepa1c1c7) cell line and antimutagenic properties towards chemical-induced mutation in Salmonella typhimurium strains TA98 and TA100. Mutagen...
متن کاملAnti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan)
Gynostemma pentaphyllum (Thunb.) Makino (GpM) (Jiaogulan) has been widely used in Chinese medicine for the treatment of several diseases, including hepatitis, diabetes and cardiovascular disease. Furthermore, GpM has recently been shown to exhibit potent anti-cancer activities. In this review, we have summarized recent research progress on the anti-cancer activities and mechanisms of action of ...
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Gynostemma pentaphyllum (Thunb.) Makino (GpM) has been widely used in traditional Chinese medicine (TCM) for the treatment of various diseases including cancer. Most previous studies have focused primarily on polar fractions of GpM for anticancer activities. In this study, a nonpolar fraction EA1.3A from GpM showed potent growth inhibitory activities against four cancer cell lines with IC50 ran...
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Background. The objective of this paper is to demonstrate the effect of Gynostemma pentaphyllum extract on mouse dermal fibroblasts. Recent studies have shown that this plant may possess great antioxidant properties, which can be very beneficial in combating oxidative stress. Methods. Gynostemma pentaphyllum extract was prepared and mouse dermal fibroblasts were obtained and cultured as per our...
متن کاملIdentification of Major Saponins from Jiaogulan Extract (Gynostemma pentaphyllum)
Jiaogulan (Gynostemma pentaphyllum; GP) contained a saponin glycoside which was related to ginseng saponin. The purpose of this study was to identify the main saponin in water extract GP compared to methanol and ethanol extract. The sample was prepared by alkaline cleavage, trimethylsilyl (TMS) derivatization and gas chromatographic-mass spectrometric (GC-MS) analysis comparison with standard g...
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ژورنال
عنوان ژورنال: The Journal of Medical Investigation
سال: 2005
ISSN: 1343-1420,1349-6867
DOI: 10.2152/jmi.52.145